APC10 Antibody, ALEXA FLUOR 555

Catalog number:	bs-12483R-A555 Buy Now
Price:	2243 €
Supplier:	MBS Recombinant Proteins
Product name:	APC10 Antibody, ALEXA FLUOR 555
Quantity:	1000ug
Related search:	apc alexa antibody fluor antibodies gene complex cdc deg

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Long name:	ALEXA FLUOR 555 Conjugated, APC10 Polyclonal Antibody
Also known as:	Anti-APC10 PAb ALEXA FLUOR 555
Category:	Conjugated Primary Antibodies
Conjugated with:	555, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	APC10
Specificity:	This is a highly specific antibody against APC10
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APC10
Gene ID Number:	10393
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	APC, APC is phosphorylated, APC is under tight control by a number of regulatory factors, APC10 also localizes to kinetochores from prophase to anaphase, APC10 binds to core APC subunits throughout the cell cycle, APC10 binds to the C-terminus of CDC27/APC3, APC10 contains a Doc1 homology domain, APC10 is localized in centrosomes and mitotic spindles, CDC20 and CDH1 directly bind to and activate the cyclin-ubiquitination activity of APCs, CDH1 and MAD2, During mitosis, In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC, Specifically, Specifically, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division, and thus activated, and to the midbody in telophase and cytokinesis, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk), including CDC20, or cyclosome, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis, thus preventing APC activation, which is a beta-sandwich structure common to many other putative E3 ubiquitin ligases, Composed of more than ten subunits
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	553nm/568nm
Synonyms:	APC10 DOC1 DKFZP564L0562
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 555, Alexa Fluor
Gene target:	APC10
Short name:	APC10 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 555
Alternative name:	ALEXA FLUOR 555, APC10 (Antibody to)
Alternative technique:	antibodies
Identity:	24077
Gene:	ANAPC10 | More about : ANAPC10
Long gene name:	anaphase promoting complex subunit 10
Locus:	4q31, 21
Discovery year:	2004-05-21
GenBank acession:	AF132794
Entrez gene record:	10393
Pubmed identfication:	10318877 11230166
RefSeq identity:	NM_014885
Classification:	Anaphase promoting complex
Havana BLAST/BLAT:	OTTHUMG00000161477

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