| Long name: |
FITC Conjugated, MISRII/AMHR2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MISRII/AMHR2 |
| Specificity: |
This is a highly specific antibody against MISRII/AMHR2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human MISRII/AMHR2 |
| Gene ID number: |
269 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2), MISR II also acts as a receptor for anti-Muellerian hormone, MISR II belongs to the protein kinase superfamily, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases, PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males, TGFB receptor subfamily and contains one protein kinase domain, TKL Ser/Thr protein kinase family, These type II receptors rylate and activate type I receptors which autophosphorylate, Upon ligand binding, then bind and activate Smad transcriptional regulators, MISR II is a 573 amino acid protein encoded by the human gene AMHR2 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MISR2 MISRII |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MISRII/AMHR2 Conjugated |
| Short name: |
FITC Conjugated, MISRII/AMHR2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
classification II (Antibody to), fluorecein coupled, MISRII/antibody to-Mullerian hormone receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AMHR and MISR2 and MISRII and MRII, AMHR2 and IDBG-36672 and ENSG00000135409 and 269, AMHR2 and IDBG-631327 and ENSBTAG00000018524 and, Amhr2 and IDBG-188637 and ENSMUSG00000023047 and 110542, Plasma membranes, this GO :0001880 and Mullerian duct regression and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005026 and transforming growth factor beta receptor activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity and also this GO :0004702 : receptor signaling protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004872 : receptor activity and also this GO :0005024 : transforming growth factor beta-activated receptor activity and also this GO :0005026 : transforming growth factor beta receptor activity, this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity, this GO :0004702 : receptor signaling protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004872 : receptor activity, this GO :0005024 : transforming growth factor beta-activated receptor activity, this GO :0005026 : transforming growth factor beta receptor activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0042562 : hormone binding, this GO :0046872 : metal ion binding, this GO :1990272 : anti-Mullerian hormone receptor activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042562 : hormone binding and also this GO :0046872 : metal ion binding and also this GO :1990272 : anti-Mullerian hormone receptor activity, transferring phosphorus-containing groups and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0042562 and hormone binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :1902613 and negative regulation of anti-Mullerian hormone signaling pathway and biological process this GO :1990262 and anti-Mullerian hormone signaling pathway and biological process this GO :1990272 and anti-Mullerian hormone receptor activity and molecular function, transforming growth factor beta receptor activity, type II, type II, type II and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, type II and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007548 and sex differentiation and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, anti-Mullerian hormone receptor |
| Identity: |
465 |
| Gene: |
AMHR2 |
More about : AMHR2 |
| Long gene name: |
anti-Mullerian hormone receptor type 2 |
| Synonyms gene name: |
anti-Mullerian hormone receptor type II |
| Synonyms name: |
Muellerian inhibiting substance type II receptor |
| Locus: |
12q13, 13 |
| Discovery year: |
1997-07-22 |
| GenBank acession: |
AF172932 |
| Entrez gene record: |
269 |
| Pubmed identfication: |
7493017 |
| RefSeq identity: |
NM_020547 |
| Classification: |
Type 2 receptor serine/threonine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000170048 |