| Long name: |
MISRII/AMHR2 Primary Polyclonal Antibody |
| Also known as: |
MISRII/AMHR2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MISRII/AMHR2 |
| Specificity: |
This is a highly specific antibody against MISRII/AMHR2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MISRII/AMHR2 |
| Gene ID number: |
269 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2), MISR II also acts as a receptor for anti-Muellerian hormone, MISR II belongs to the protein kinase superfamily, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases, PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males, TGFB receptor subfamily and contains one protein kinase domain, TKL Ser/Thr protein kinase family, These type II receptors rylate and activate type I receptors which autophosphorylate, Upon ligand binding, then bind and activate Smad transcriptional regulators, MISR II is a 573 amino acid protein encoded by the human gene AMHR2 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AMHR2, AMHR2_HUMAN, Anti-Muellerian hormone type II receptor, Anti-Muellerian hormone type-2 receptor, MGC141312, MIS type II receptor, MISRII, MRII, Muellerian hormone type 2 receptor, Muellerian hormone type II receptor, Mullerian hormone receptor type II, AMH type II receptor |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MISRII/AMHR2 |
| Short name: |
MISRII/AMHR2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
classification II (Antibody to), MISRII/antibody to-Mullerian hormone receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AMHR and MISR2 and MISRII and MRII, AMHR2 and IDBG-36672 and ENSG00000135409 and 269, AMHR2 and IDBG-631327 and ENSBTAG00000018524 and, Amhr2 and IDBG-188637 and ENSMUSG00000023047 and 110542, Plasma membranes, this GO :0001880 and Mullerian duct regression and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005026 and transforming growth factor beta receptor activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity and also this GO :0004702 : receptor signaling protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004872 : receptor activity and also this GO :0005024 : transforming growth factor beta-activated receptor activity and also this GO :0005026 : transforming growth factor beta receptor activity, this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity, this GO :0004702 : receptor signaling protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004872 : receptor activity, this GO :0005024 : transforming growth factor beta-activated receptor activity, this GO :0005026 : transforming growth factor beta receptor activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0042562 : hormone binding, this GO :0046872 : metal ion binding, this GO :1990272 : anti-Mullerian hormone receptor activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042562 : hormone binding and also this GO :0046872 : metal ion binding and also this GO :1990272 : anti-Mullerian hormone receptor activity, transferring phosphorus-containing groups and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0042562 and hormone binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :1902613 and negative regulation of anti-Mullerian hormone signaling pathway and biological process this GO :1990262 and anti-Mullerian hormone signaling pathway and biological process this GO :1990272 and anti-Mullerian hormone receptor activity and molecular function, transforming growth factor beta receptor activity, type II, type II, type II and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, type II and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007548 and sex differentiation and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, anti-Mullerian hormone receptor |
| Identity: |
465 |
| Gene: |
AMHR2 |
More about : AMHR2 |
| Long gene name: |
anti-Mullerian hormone receptor type 2 |
| Synonyms gene name: |
anti-Mullerian hormone receptor type II |
| Synonyms: |
MISR2 MISRII |
| Synonyms name: |
Muellerian inhibiting substance type II receptor |
| Locus: |
12q13, 13 |
| Discovery year: |
1997-07-22 |
| GenBank acession: |
AF172932 |
| Entrez gene record: |
269 |
| Pubmed identfication: |
7493017 |
| RefSeq identity: |
NM_020547 |
| Classification: |
Type 2 receptor serine/threonine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000170048 |