| Long name: |
ALEXA FLUOR 594 Conjugated, SPOCK1/Testican 1 Polyclonal Antibody |
| Also known as: |
Anti-SPOCK1/Testican 1 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SPOCK1/Testican 1 |
| Specificity: |
This is a highly specific antibody against SPOCK1/Testican 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPOCK1/Testican 1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
After a neural injury, Expression of Testicans is detected in a variety of tissues, Family members include Testican-1, Most Testicans inhibit MT-MMPs, Testican-1 expression is upregulated in astrocyte cells in order to inhibit the ability of the protein Neuro-2a to form neurite extensions, Testican-1 is also a component of joint and of the growth plate cartilage that may participate in the regulation of matrix turnover, Testican-1 is specifically expressed in the thalamus of the brain, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, also designated the BM-40/SPARC/osteonectin family, and is upregulated in activated astroglial cells of the cerebrum where it mediates neuronal attachment and matrix metalloproteinase activation, but is most abundant in brain, calcium-binding, designated N-Tes, extracellular, is composed of highly conserved, such as a cerebral stroke, sulfate proteoglycans, thereby inhibiting the activity of pro-MMP-2, The Testican family |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
testican-1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
SPOCK1/Testican 1 |
| Short name: |
SPOCK1/Testican 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, acidic, cwcv and kazal-like domains proteoglycan (testican) 1/Testican 1 (Antibody to), cysteine-rich (osteonectin)/osteonectin, secreted protein |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, SPOCK and TESTICAN and TIC1, SPOCK1 and IDBG-46103 and ENSG00000152377 and 6695, SPOCK1 and IDBG-645860 and ENSBTAG00000003502 and 511211, Spock1 and IDBG-157690 and ENSMUSG00000056222 and 20745, cwcv and kazal-like domains proteoglycan (testican) 1, metalloendopeptidase inhibitor activity, this GO :0001558 and regulation of cell growth and biological process this GO :0001764 and neuron migration and biological process this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0004869 and cysteine-type endopeptidase inhibitor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0008191 and metalloendopeptidase inhibitor activity and molecular function this GO :0010812 and negative regulation of cell-substrate adhesion and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0016528 and sarcoplasm and cellular component this GO :0021953 and central nervous system neuron differentiation and biological process this GO :0022008 and neurogenesis and biological process this GO :0031594 and neuromuscular junction and cellular component this GO :0033268 and node of Ranvier and cellular component, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0004869 : cysteine-type endopeptidase inhibitor activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008191 : metalloendopeptidase inhibitor activity, this GO :0004869 : cysteine-type endopeptidase inhibitor activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008191 : metalloendopeptidase inhibitor activity, sparc/osteonectin |
| Identity: |
11251 |
| Gene: |
SPOCK1 |
More about : SPOCK1 |
| Long gene name: |
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 |
| Synonyms gene: |
TIC1 SPOCK |
| Synonyms gene name: |
cwcv and kazal-like domains proteoglycan (testican) , sparc/osteonectin |
| Locus: |
5q31, 2 |
| Discovery year: |
1995-10-02 |
| GenBank acession: |
AF231124 |
| Entrez gene record: |
6695 |
| Pubmed identfication: |
9545645 |
| RefSeq identity: |
NM_004598 |
| Classification: |
SPARC family |
| Havana BLAST/BLAT: |
OTTHUMG00000129157 |