| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SPOCK2/Testican 2 |
| Specificity: |
This antibody reacts specifically with SPOCK2/Testican 2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SPOCK2/Testican 2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Expression of Testicans is detected in a variety of tissues, Family members include Testican-1, Most Testicans inhibit MT-MMPs, Testican-2, Testican-2 halts neurite growth from cerebellar neurons and may be involved in regu-lating the development of the CNS, Testican-2 is expressed in the central nervous system (CNS), Testican-2 is unique in that it actually abolishes the inhibition of MT-MMPs by other testican family members and specifically inactivates N-Tes by binding to its COOH-terminal extracellular calcium-binding domain, Testican-3 and an amino-terminal splice variant of Testican-3, also designated the BM-40/SPARC/osteonectin family, and is also found in lung and testis, but is most abundant in brain, calcium-binding, cerebellum and medulla, cerebral cortex, designated N-Tes, extracellular, hippocampus, is composed of highly conserved, sulfate proteoglycans, thalamus, thereby inhibiting the activity of pro-MMP-2, with widespread expression in the olfactory bulb, The Testican family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0275 testican-2 |
| Also known as: |
SPOCK2/Testican 2 Polyclonal Antibody |
| Other name: |
Anti-SPOCK2/Testican 2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SPOCK2/Testican 2 |
| Short name: |
Anti-SPOCK2/Testican 2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SPOCK2/Testican 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13564 |
| Gene: |
SPOCK2 |
More about : SPOCK2 |
| Long gene name: |
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 |
| Synonyms gene name: |
cwcv and kazal-like domains proteoglycan (testican) 2 , sparc/osteonectin |
| Locus: |
10q22, 1 |
| Discovery year: |
2003-01-24 |
| GenBank acession: |
AJ001453 |
| Entrez gene record: |
9806 |
| Pubmed identfication: |
10386950 |
| Classification: |
SPARC family |
| Havana BLAST/BLAT: |
OTTHUMG00000018430 |