| Long name: |
FITC Conjugated, SPOCK1/Testican 1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SPOCK1/Testican 1 |
| Specificity: |
This is a highly specific antibody against SPOCK1/Testican 1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SPOCK1/Testican 1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
After a neural injury, Expression of Testicans is detected in a variety of tissues, Family members include Testican-1, Most Testicans inhibit MT-MMPs, Testican-1 expression is upregulated in astrocyte cells in order to inhibit the ability of the protein Neuro-2a to form neurite extensions, Testican-1 is also a component of joint and of the growth plate cartilage that may participate in the regulation of matrix turnover, Testican-1 is specifically expressed in the thalamus of the brain, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, also designated the BM-40/SPARC/osteonectin family, and is upregulated in activated astroglial cells of the cerebrum where it mediates neuronal attachment and matrix metalloproteinase activation, but is most abundant in brain, calcium-binding, designated N-Tes, extracellular, is composed of highly conserved, such as a cerebral stroke, sulfate proteoglycans, thereby inhibiting the activity of pro-MMP-2, The Testican family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
testican-1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SPOCK1/Testican 1 Conjugated |
| Short name: |
FITC Conjugated, SPOCK1/Testican 1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
acidic, cwcv and kazal-like domains proteoglycan (testican) 1/Testican 1 (Antibody to), cysteine-rich (osteonectin)/osteonectin, fluorecein coupled, secreted protein |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, SPOCK and TESTICAN and TIC1, SPOCK1 and IDBG-46103 and ENSG00000152377 and 6695, SPOCK1 and IDBG-645860 and ENSBTAG00000003502 and 511211, Spock1 and IDBG-157690 and ENSMUSG00000056222 and 20745, cwcv and kazal-like domains proteoglycan (testican) 1, metalloendopeptidase inhibitor activity, this GO :0001558 and regulation of cell growth and biological process this GO :0001764 and neuron migration and biological process this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0004869 and cysteine-type endopeptidase inhibitor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0008191 and metalloendopeptidase inhibitor activity and molecular function this GO :0010812 and negative regulation of cell-substrate adhesion and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0016528 and sarcoplasm and cellular component this GO :0021953 and central nervous system neuron differentiation and biological process this GO :0022008 and neurogenesis and biological process this GO :0031594 and neuromuscular junction and cellular component this GO :0033268 and node of Ranvier and cellular component, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0004869 : cysteine-type endopeptidase inhibitor activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008191 : metalloendopeptidase inhibitor activity, this GO :0004869 : cysteine-type endopeptidase inhibitor activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008191 : metalloendopeptidase inhibitor activity, sparc/osteonectin |
| Identity: |
11251 |
| Gene: |
SPOCK1 |
More about : SPOCK1 |
| Long gene name: |
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 |
| Synonyms gene: |
TIC1 SPOCK |
| Synonyms gene name: |
cwcv and kazal-like domains proteoglycan (testican) , sparc/osteonectin |
| Locus: |
5q31, 2 |
| Discovery year: |
1995-10-02 |
| GenBank acession: |
AF231124 |
| Entrez gene record: |
6695 |
| Pubmed identfication: |
9545645 |
| RefSeq identity: |
NM_004598 |
| Classification: |
SPARC family |
| Havana BLAST/BLAT: |
OTTHUMG00000129157 |