| Long name: |
FITC Conjugated, CRBN Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CRBN |
| Specificity: |
This is a highly specific antibody against CRBN |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CRBN |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, CRBN functions are thought to be related to energy metabolism, Defects in the CRBN gene are associated with mild mental retardation, Localized to the cytoplasm, The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, learning and memory, such as the hippocampus, CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MRT2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CRBN Conjugated |
| Short name: |
FITC Conjugated, CRBN Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CRBN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30185 |
| Gene: |
CRBN |
More about : CRBN |
| Long gene name: |
cereblon |
| Synonyms gene: |
MRT2A |
| Synonyms gene name: |
2A , autosomal recessive, mental retardation, non-syndromic |
| Locus: |
3p26, 2 |
| Discovery year: |
2004-05-19 |
| GenBank acession: |
BC017419 |
| Entrez gene record: |
51185 |
| Pubmed identfication: |
15557513 |
| RefSeq identity: |
NM_016302 |
| Havana BLAST/BLAT: |
OTTHUMG00000090261 |