| Long name: |
ALEXA FLUOR 647 Conjugated, CRBN Polyclonal Antibody |
| Also known as: |
Anti-CRBN PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CRBN |
| Specificity: |
This is a highly specific antibody against CRBN |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRBN |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, CRBN functions are thought to be related to energy metabolism, Defects in the CRBN gene are associated with mild mental retardation, Localized to the cytoplasm, The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, learning and memory, such as the hippocampus, CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MRT2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CRBN Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
CRBN |
| Short name: |
CRBN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, CRBN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30185 |
| Gene: |
CRBN |
More about : CRBN |
| Long gene name: |
cereblon |
| Synonyms gene: |
MRT2A |
| Synonyms gene name: |
2A , autosomal recessive, mental retardation, non-syndromic |
| Locus: |
3p26, 2 |
| Discovery year: |
2004-05-19 |
| GenBank acession: |
BC017419 |
| Entrez gene record: |
51185 |
| Pubmed identfication: |
15557513 |
| RefSeq identity: |
NM_016302 |
| Havana BLAST/BLAT: |
OTTHUMG00000090261 |