| Long name: |
Cy3 Conjugated, CRBN Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CRBN |
| Specificity: |
This is a highly specific antibody against CRBN |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CRBN |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, CRBN functions are thought to be related to energy metabolism, Defects in the CRBN gene are associated with mild mental retardation, Localized to the cytoplasm, The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, learning and memory, such as the hippocampus, CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
MRT2 |
| Properties: |
1 of the CRBN Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CRBN Conjugated |
| Short name: |
Conjugated, CRBN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, CRBN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30185 |
| Gene: |
CRBN |
More about : CRBN |
| Long gene name: |
cereblon |
| Synonyms gene: |
MRT2A |
| Synonyms gene name: |
2A , autosomal recessive, mental retardation, non-syndromic |
| Locus: |
3p26, 2 |
| Discovery year: |
2004-05-19 |
| GenBank acession: |
BC017419 |
| Entrez gene record: |
51185 |
| Pubmed identfication: |
15557513 |
| RefSeq identity: |
NM_016302 |
| Havana BLAST/BLAT: |
OTTHUMG00000090261 |