| Long name: |
FITC Conjugated, CHMP2B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CHMP2B |
| Specificity: |
This is a highly specific antibody against CHMP2B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CHMP2B |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, CHMP2B, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex, Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3), II or III complexes, These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), Widely expressed in brain, also known as CHMP2, and are also required for the formation of these bodies, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins, commonly designated CHMPs, heart, is a 213 amino acid cytosolic protein, lung, pancreas, placenta and leukocytes, skeletal muscle, small intestine, 5 or vacuolar protein-sorting-associated protein 2-2, The charged multivesicular body proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
DKFZP564O123 CHMP2, 5 VPS2B |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CHMP2B Conjugated |
| Short name: |
FITC Conjugated, CHMP2B Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CHMP2B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24537 |
| Gene: |
CHMP2B |
More about : CHMP2B |
| Long gene name: |
charged multivesicular body protein 2B |
| Synonyms gene name: |
chromatin modifying protein 2B |
| Synonyms name: |
VPS2 homolog B (S, cerevisiae) |
| Locus: |
3p11, 2 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
BC001553 |
| Entrez gene record: |
25978 |
| Pubmed identfication: |
11559748 |
| RefSeq identity: |
NM_014043 |
| Classification: |
Charged multivesicular body proteins ESCRT-III |
| Havana BLAST/BLAT: |
OTTHUMG00000158982 |