| Long name: |
Cy3 Conjugated, CHMP2B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CHMP2B |
| Specificity: |
This is a highly specific antibody against CHMP2B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CHMP2B |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, CHMP2B, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex, Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3), II or III complexes, These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), Widely expressed in brain, also known as CHMP2, and are also required for the formation of these bodies, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins, commonly designated CHMPs, heart, is a 213 amino acid cytosolic protein, lung, pancreas, placenta and leukocytes, skeletal muscle, small intestine, 5 or vacuolar protein-sorting-associated protein 2-2, The charged multivesicular body proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
DKFZP564O123 CHMP2, 5 VPS2B |
| Properties: |
1 of the CHMP2B Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CHMP2B Conjugated |
| Short name: |
Conjugated, CHMP2B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, CHMP2B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24537 |
| Gene: |
CHMP2B |
More about : CHMP2B |
| Long gene name: |
charged multivesicular body protein 2B |
| Synonyms gene name: |
chromatin modifying protein 2B |
| Synonyms name: |
VPS2 homolog B (S, cerevisiae) |
| Locus: |
3p11, 2 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
BC001553 |
| Entrez gene record: |
25978 |
| Pubmed identfication: |
11559748 |
| RefSeq identity: |
NM_014043 |
| Classification: |
Charged multivesicular body proteins ESCRT-III |
| Havana BLAST/BLAT: |
OTTHUMG00000158982 |