| Long name: |
CHMP2B Primary Polyclonal Antibody |
| Also known as: |
CHMP2B PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CHMP2B |
| Specificity: |
This is a highly specific antibody against CHMP2B |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHMP2B |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, CHMP2B, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex, Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3), II or III complexes, These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), Widely expressed in brain, also known as CHMP2, and are also required for the formation of these bodies, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins, commonly designated CHMPs, heart, is a 213 amino acid cytosolic protein, lung, pancreas, placenta and leukocytes, skeletal muscle, small intestine, 5 or vacuolar protein-sorting-associated protein 2-2, The charged multivesicular body proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CHM2B_HUMAN, CHMP2, CHMP2b, Chromatin modying protein 2b, Chromatin-modying protein 2b, DMT1, VPS2 homolog B, VPS2B, Vacuolar protein sorting 2-2, Vacuolar protein sorting-associated protein 2-2, Vps2-2, hVps2-2, 5, Charged multivesicular body protein 2b |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CHMP2B |
| Short name: |
CHMP2B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CHMP2B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24537 |
| Gene: |
CHMP2B |
More about : CHMP2B |
| Long gene name: |
charged multivesicular body protein 2B |
| Synonyms gene name: |
chromatin modifying protein 2B |
| Synonyms: |
DKFZP564O123 CHMP2, 5 VPS2B |
| Synonyms name: |
VPS2 homolog B (S, cerevisiae) |
| Locus: |
3p11, 2 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
BC001553 |
| Entrez gene record: |
25978 |
| Pubmed identfication: |
11559748 |
| RefSeq identity: |
NM_014043 |
| Classification: |
Charged multivesicular body proteins ESCRT-III |
| Havana BLAST/BLAT: |
OTTHUMG00000158982 |