| Long name: |
ALEXA FLUOR 488 Conjugated, CHMP2B Polyclonal Antibody |
| Also known as: |
Anti-CHMP2B PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CHMP2B |
| Specificity: |
This is a highly specific antibody against CHMP2B |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHMP2B |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, CHMP2B, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex, Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3), II or III complexes, These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), Widely expressed in brain, also known as CHMP2, and are also required for the formation of these bodies, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins, commonly designated CHMPs, heart, is a 213 amino acid cytosolic protein, lung, pancreas, placenta and leukocytes, skeletal muscle, small intestine, 5 or vacuolar protein-sorting-associated protein 2-2, The charged multivesicular body proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
DKFZP564O123 CHMP2, 5 VPS2B |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CHMP2B Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CHMP2B |
| Short name: |
CHMP2B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, CHMP2B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24537 |
| Gene: |
CHMP2B |
More about : CHMP2B |
| Long gene name: |
charged multivesicular body protein 2B |
| Synonyms gene name: |
chromatin modifying protein 2B |
| Synonyms name: |
VPS2 homolog B (S, cerevisiae) |
| Locus: |
3p11, 2 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
BC001553 |
| Entrez gene record: |
25978 |
| Pubmed identfication: |
11559748 |
| RefSeq identity: |
NM_014043 |
| Classification: |
Charged multivesicular body proteins ESCRT-III |
| Havana BLAST/BLAT: |
OTTHUMG00000158982 |