| Long name: |
Biotin Conjugated, HAP40/F8a Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HAP40/F8a |
| Specificity: |
This is a highly specific antibody against HAP40/F8a |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HAP40 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
HAP40, HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes, Huntingtin interacts with a variety of proteins including HAP1, Rab5 and HIP1, Specifically, The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins, The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism, glyceraldehyde phosphate dehydrogenase (GAPDH), this complex regulates endosome motility, which leads to Huntingtinâ, which may be a key event of the pathogenetic process leading to neurodegeneration in HD, &euro, &trade, The Huntingtin protein contains a polyglutamine region, s disease (HD) when the number of glutamine repeats exceeds thirty-five |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Coagulation factor VIII associated intronic transcript 1, CpG island protein, DXS522E, F8A1, F8A2, F8A3, F8I2_HUMAN, F8a, Factor 8 associated protein, Factor 8 intron 22 protein, Factor VIII associated protein, Factor VIII intron 22 protein, huntingtin associated protein 40, Coagulation factor 8 associated intronic transcript 1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HAP40/F8a Conjugated |
| Short name: |
Conjugated, HAP40/F8a Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, HAP40/F8a (Antibody to) |
| Alternative technique: |
antibodies |