| Long name: |
HAP40/F8a Primary Polyclonal Antibody |
| Also known as: |
HAP40/F8a PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HAP40/F8a |
| Specificity: |
This is a highly specific antibody against HAP40/F8a |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HAP40 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
HAP40, HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes, Huntingtin interacts with a variety of proteins including HAP1, Rab5 and HIP1, Specifically, The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins, The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism, glyceraldehyde phosphate dehydrogenase (GAPDH), this complex regulates endosome motility, which leads to Huntingtinâ, which may be a key event of the pathogenetic process leading to neurodegeneration in HD, &euro, &trade, The Huntingtin protein contains a polyglutamine region, s disease (HD) when the number of glutamine repeats exceeds thirty-five |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Coagulation factor VIII associated intronic transcript 1, CpG island protein, DXS522E, F8A1, F8A2, F8A3, F8I2_HUMAN, F8a, Factor 8 associated protein, Factor 8 intron 22 protein, Factor VIII associated protein, Factor VIII intron 22 protein, huntingtin associated protein 40, Coagulation factor 8 associated intronic transcript 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HAP40/F8a |
| Short name: |
HAP40/F8a Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HAP40/F8a (Antibody to) |
| Alternative technique: |
antibodies |