| Long name: |
ALEXA FLUOR 350 Conjugated, HAP40/F8a Polyclonal Antibody |
| Also known as: |
Anti-HAP40/F8a PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HAP40/F8a |
| Specificity: |
This is a highly specific antibody against HAP40/F8a |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HAP40 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
HAP40, HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes, Huntingtin interacts with a variety of proteins including HAP1, Rab5 and HIP1, Specifically, The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins, The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism, glyceraldehyde phosphate dehydrogenase (GAPDH), this complex regulates endosome motility, which leads to Huntingtinâ, which may be a key event of the pathogenetic process leading to neurodegeneration in HD, &euro, &trade, The Huntingtin protein contains a polyglutamine region, s disease (HD) when the number of glutamine repeats exceeds thirty-five |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
Coagulation factor VIII associated intronic transcript 1, CpG island protein, DXS522E, F8A1, F8A2, F8A3, F8I2_HUMAN, F8a, Factor 8 associated protein, Factor 8 intron 22 protein, Factor VIII associated protein, Factor VIII intron 22 protein, huntingtin associated protein 40, Coagulation factor 8 associated intronic transcript 1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
HAP40/F8a |
| Short name: |
HAP40/F8a Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, HAP40/F8a (Antibody to) |
| Alternative technique: |
antibodies |