| Long name: |
FITC Conjugated, KIBRA Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KIBRA |
| Specificity: |
This is a highly specific antibody against KIBRA |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
370-420/1113 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human KIBRA |
| Gene ID number: |
23286 |
| Swiss Prot: |
Q8IX03 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a substrate for PRKCZ, Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation, Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, Modulates directional migration of podocytes, Plays a role in cognition and memory performance, Regulates collagen-stimulated activation of the ERK/MAPK cascade, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis, Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
KIBRA KIAA0869 PPP1R168 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
KIBRA Conjugated |
| Short name: |
FITC Conjugated, KIBRA Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, KIBRA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29435 |
| Gene: |
WWC1 |
More about : WWC1 |
| Long gene name: |
WW and C2 domain containing 1 |
| Synonyms gene name: |
C2 and coiled-coil domain containing 1 , WW |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 168 |
| Locus: |
5q34 |
| Discovery year: |
2006-02-22 |
| GenBank acession: |
AF506799 |
| Entrez gene record: |
23286 |
| Pubmed identfication: |
10048485 12559952 |
| RefSeq identity: |
NM_015238 |
| Classification: |
Protein phosphatase 1 regulatory subunits C2 and WW domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130408 |