| Long name: |
ALEXA FLUOR 488 Conjugated, KIBRA Polyclonal Antibody |
| Also known as: |
Anti-KIBRA PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KIBRA |
| Specificity: |
This is a highly specific antibody against KIBRA |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
370-420/1113 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KIBRA |
| Gene ID Number: |
23286 |
| Swiss Prot: |
Q8IX03 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as a substrate for PRKCZ, Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation, Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, Modulates directional migration of podocytes, Plays a role in cognition and memory performance, Regulates collagen-stimulated activation of the ERK/MAPK cascade, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis, Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
KIBRA KIAA0869 PPP1R168 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the KIBRA Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
KIBRA |
| Short name: |
KIBRA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, KIBRA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29435 |
| Gene: |
WWC1 |
More about : WWC1 |
| Long gene name: |
WW and C2 domain containing 1 |
| Synonyms gene name: |
C2 and coiled-coil domain containing 1 , WW |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 168 |
| Locus: |
5q34 |
| Discovery year: |
2006-02-22 |
| GenBank acession: |
AF506799 |
| Entrez gene record: |
23286 |
| Pubmed identfication: |
10048485 12559952 |
| RefSeq identity: |
NM_015238 |
| Classification: |
Protein phosphatase 1 regulatory subunits C2 and WW domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130408 |