| Long name: |
KIBRA Primary Polyclonal Antibody |
| Also known as: |
KIBRA PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
KIBRA |
| Specificity: |
This is a highly specific antibody against KIBRA |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
370-420/1113 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KIBRA |
| Gene ID number: |
23286 |
| Swiss Prot: |
Q8IX03 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a substrate for PRKCZ, Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation, Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, Modulates directional migration of podocytes, Plays a role in cognition and memory performance, Regulates collagen-stimulated activation of the ERK/MAPK cascade, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis, Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HBEBP3, HBEBP36, HBeAg-binding protein 3, KIAA0869, Kidney and brain protein, MEMRYQTL, PPP1R168, Protein KIBRA, WW domain-containing protein 1, WWC1, KIBRA |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
KIBRA |
| Short name: |
KIBRA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
KIBRA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29435 |
| Gene: |
WWC1 |
More about : WWC1 |
| Long gene name: |
WW and C2 domain containing 1 |
| Synonyms gene name: |
C2 and coiled-coil domain containing 1 , WW |
| Synonyms: |
KIBRA KIAA0869 PPP1R168 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 168 |
| Locus: |
5q34 |
| Discovery year: |
2006-02-22 |
| GenBank acession: |
AF506799 |
| Entrez gene record: |
23286 |
| Pubmed identfication: |
10048485 12559952 |
| RefSeq identity: |
NM_015238 |
| Classification: |
Protein phosphatase 1 regulatory subunits C2 and WW domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130408 |