| Catalog number: | bs-11474R-HRP |
|---|---|
| Price: | 1613 € |
| Supplier: | novo |
| Product name: | Repulsive Guidance Molecule B Antibody, HRP Conjugated |
| Quantity: | 500 µg |
| Related search: |
| Long name: | HRP Conjugated, Repulsive Guidance Molecule B Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | HRP Conjugated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | RGMB/Repulsive Guidance Molecule B |
| Specificity: | This is a highly specific antibody against RGMB/Repulsive Guidance Molecule B |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule B |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Defects in the gene encoding for RGMc causes the autosomal recessive disorder juvenile hemochromatosis (JH), Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness, RGM have been implicated in both axonal guidance and neural tube closure but as opposed to for ephrins, RGMa and RGMb, RGMc, The RGM proteins are attached to the membrane by a GPI-anchor, They are repulsive for a group of axons, Two members of this family, also known as Hemojuvelin, are expressed in the nervous system, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut, netrins and slits, no receptor mechanism for RGM activation has been defined, semaphorins, those from the temporal half of the retina, The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | DRG11-responsive axonal guidance and outgrowth of neurite, RGM b, RGM domain family member B, RGMB_HUMAN, Repulsive Guidance Molecule B, Rgmb, Dragon |
| Properties: | Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase  |
| Description: | present in lysates used as reference for ELISA quantification of these molecules and their subunits, Whole adhesion and interacting molecules are  |
| Gene target: | Repulsive Guidance Molecule B Conjugated |
| Short name: | Conjugated, Repulsive Guidance Molecule B Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | HRP |
| Alternative name: | horseradish peroxidase coupled, Repulsive Guidance Molecule B (Antibody to) |
| Alternative technique: | antibodies |
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