Repulsive Guidance Molecule B Antibody, Cy5 Conjugated

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Catalog number: bs-11474R-Cy5
Price: 1613 €
Supplier: novo
Product name: Repulsive Guidance Molecule B Antibody, Cy5 Conjugated
Quantity: 500 µg
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More details :

Long name: Cy5 Conjugated, Repulsive Guidance Molecule B Antibody
Category: Conjugated Primary Antibodies
Conjugation: 5, Cy5
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: RGMB/Repulsive Guidance Molecule B
Specificity: This is a highly specific antibody against RGMB/Repulsive Guidance Molecule B
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule B
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Defects in the gene encoding for RGMc causes the autosomal recessive disorder juvenile hemochromatosis (JH), Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness, RGM have been implicated in both axonal guidance and neural tube closure but as opposed to for ephrins, RGMa and RGMb, RGMc, The RGM proteins are attached to the membrane by a GPI-anchor, They are repulsive for a group of axons, Two members of this family, also known as Hemojuvelin, are expressed in the nervous system, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut, netrins and slits, no receptor mechanism for RGM activation has been defined, semaphorins, those from the temporal half of the retina, The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 625, 650nm/670nm
Synonyms: DRG11-responsive axonal guidance and outgrowth of neurite, RGM b, RGM domain family member B, RGMB_HUMAN, Repulsive Guidance Molecule B, Rgmb, Dragon
Properties: Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Description: present in lysates used as reference for ELISA quantification of these molecules and their subunits, Whole adhesion and interacting molecules are 
Gene target: Repulsive Guidance Molecule B Conjugated
Short name: Conjugated, Repulsive Guidance Molecule B Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Cy5
Alternative name: cyanine 5 coupled, Repulsive Guidance Molecule B (Antibody to)
Alternative technique: antibodies

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