| Catalog number: | bs-11473R-Cy3 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | RGMA Antibody, Cy3 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy3 Conjugated, RGMA Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | cy3 conjugation kit |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | RGMA |
| Specificity: | This is a highly specific antibody against RGMA |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 340-390/450 |
| Subcellular location: | Cell membrane |
| Source: | KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule A |
| Gene ID number: | 56963 |
| Swiss Prot: | Q96B86 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, Furthermore, It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway, Regulates cephalic neural tube closure, SMAD5, and SMAD8, and the formation of mature synapses, inhibits neurite outgrowth and cortical neuron branching, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition, Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 512, 550nm/570, 615nm |
| Synonyms: | RGM RGMa |
| Properties: | 1 of the RGMA Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | RGMA Conjugated |
| Short name: | Conjugated, RGMA Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy3 |
| Alternative name: | cyanine 3 coupled, RGMA (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 30308 |
| Gene: | RGMA | More about : RGMA |
| Long gene name: | repulsive guidance molecule family member a |
| Synonyms gene name: | RGM domain family, member A |
| Locus: | 15q26, 1 |
| Discovery year: | 2004-02-04 |
| GenBank acession: | AL390083 |
| Entrez gene record: | 56963 |
| Pubmed identfication: | 15975920 |
| RefSeq identity: | NM_020211 |
| Havana BLAST/BLAT: | OTTHUMG00000171781 |
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