| Catalog number: | bs-11473R-A555 |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | RGMA Antibody, ALEXA FLUOR 555 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, RGMA Polyclonal Antibody |
|---|---|
| Also known as: | Anti-RGMA PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | RGMA |
| Specificity: | This is a highly specific antibody against RGMA |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 340-390/450 |
| Subcellular location: | Cell membrane |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule A |
| Gene ID Number: | 56963 |
| Swiss Prot: | Q96B86 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, Furthermore, It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway, Regulates cephalic neural tube closure, SMAD5, and SMAD8, and the formation of mature synapses, inhibits neurite outgrowth and cortical neuron branching, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition, Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | RGM RGMa |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | RGMA |
| Short name: | RGMA Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, RGMA (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 30308 |
| Gene: | RGMA | More about : RGMA |
| Long gene name: | repulsive guidance molecule family member a |
| Synonyms gene name: | RGM domain family, member A |
| Locus: | 15q26, 1 |
| Discovery year: | 2004-02-04 |
| GenBank acession: | AL390083 |
| Entrez gene record: | 56963 |
| Pubmed identfication: | 15975920 |
| RefSeq identity: | NM_020211 |
| Havana BLAST/BLAT: | OTTHUMG00000171781 |
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