| Catalog number: | bs-11473R |
|---|---|
| Price: | 602 € |
| Supplier: | genways |
| Product name: | RGMA Antibody |
| Quantity: | 1 vial |
| Related search: |
| Long name: | RGMA Primary Polyclonal Antibody |
|---|---|
| Also known as: | RGMA PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | RGMA |
| Specificity: | This is a highly specific antibody against RGMA |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 340-390/450 |
| Subcellular location: | Cell membrane |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule A |
| Gene ID number: | 56963 |
| Swiss Prot: | Q96B86 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, Furthermore, It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway, Regulates cephalic neural tube closure, SMAD5, and SMAD8, and the formation of mature synapses, inhibits neurite outgrowth and cortical neuron branching, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition, Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | RGM domain family member A, RGMA, Repulsive guidance molecule A, RGM |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | RGMA |
| Short name: | RGMA Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | RGMA (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 30308 |
| Gene: | RGMA | More about : RGMA |
| Long gene name: | repulsive guidance molecule family member a |
| Synonyms gene name: | RGM domain family, member A |
| Synonyms: | RGM RGMa |
| Locus: | 15q26, 1 |
| Discovery year: | 2004-02-04 |
| GenBank acession: | AL390083 |
| Entrez gene record: | 56963 |
| Pubmed identfication: | 15975920 |
| RefSeq identity: | NM_020211 |
| Havana BLAST/BLAT: | OTTHUMG00000171781 |
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