RGMA Antibody

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Catalog number: bs-11473R
Price: 602 €
Supplier: genways
Product name: RGMA Antibody
Quantity: 1 vial
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Long name: RGMA Primary Polyclonal Antibody
Also known as: RGMA PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: RGMA
Specificity: This is a highly specific antibody against RGMA
Modification(s): None
Modification site(s): Unmodified antibody
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 340-390/450
Subcellular location: Cell membrane
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule A
Gene ID number: 56963
Swiss Prot: Q96B86
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, Furthermore, It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway, Regulates cephalic neural tube closure, SMAD5, and SMAD8, and the formation of mature synapses, inhibits neurite outgrowth and cortical neuron branching, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition, Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: RGM domain family member A, RGMA, Repulsive guidance molecule A, RGM
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: RGMA
Short name: RGMA Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: RGMA (Antibody to)
Alternative technique: antibodies
Identity: 30308
Gene: RGMA | More about : RGMA
Long gene name: repulsive guidance molecule family member a
Synonyms gene name: RGM domain family, member A
Synonyms: RGM RGMa
Locus: 15q26, 1
Discovery year: 2004-02-04
GenBank acession: AL390083
Entrez gene record: 56963
Pubmed identfication: 15975920
RefSeq identity: NM_020211
Havana BLAST/BLAT: OTTHUMG00000171781

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