| Long name: |
ALEXA FLUOR 647 Conjugated, HSD17B4 Polyclonal Antibody |
| Also known as: |
Anti-HSD17B4 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HSD17B4 |
| Specificity: |
This is a highly specific antibody against HSD17B4 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSD17B4 Enoyl-CoA hydratase 2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation, 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6, 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life, D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV, It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body, It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain, They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period, 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MFE-2 DBP SDR8C1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the HSD17B4 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
HSD17B4 |
| Short name: |
HSD17B4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, HSD17B4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5213 |
| Gene: |
HSD17B4 |
More about : HSD17B4 |
| Long gene name: |
hydroxysteroid 17-beta dehydrogenase 4 |
| Synonyms gene name: |
hydroxysteroid (17-beta) dehydrogenase 4 |
| Synonyms name: |
17beta-estradiol dehydrogenase type IV peroxisomal multifunctional protein 2 17-beta-HSD IV 17-beta-hydroxysteroid dehydrogenase 4 D-bifunctional protein, member 1 , peroxisomal D-3-hydroxyacyl-CoA dehydratase 3-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase beta-keto-reductase beta-hydroxyacyl dehydrogenase short chain dehydrogenase/reductase family 8C, 7-alpha |
| Locus: |
5q23, 1 |
| Discovery year: |
1994-09-14 |
| Entrez gene record: |
3295 |
| Pubmed identfication: |
8938456 19027726 |
| RefSeq identity: |
NM_000414 |
| Classification: |
Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000128899 |