| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
17-beta-Hydroxysteroid dehydrogenase 4 (HSD17B4) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the 17-beta-Hydroxysteroid dehydrogenase 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This 17-beta-Hydroxysteroid dehydrogenase 4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
F5HE57 |
| Purity: |
Antigen affinity |
| Description: |
In contrast, It was first identified as a 17-beta-estradiol dehydrogenase, Peroxisomal beta-oxidation of fatty acids is catalyzed by 3 enzymes: acyl-CoA oxidase, The D- and L-bifunctional proteins have different substrate specificities, The D-bifunctional protein catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids and also acts in shortening cholesterol for bile acid formation, and 3-ketoacyl-CoA thiolase, the D-bifunctional enzyme with enoyl-CoA-hydratase and D-3-hydroxyacyl-CoA dehydrogenase activity, the L-specific bifunctional protein does not have the latter 2 activities, The HSD17B4 gene encodes an enzyme involved in peroxisomal fatty acid beta-oxidation |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human HSD17B4 (NIMLSQKLQMILKDYAKL) was used as the immunogen for this 17-beta-Hydroxysteroid dehydrogenase 4 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the 17-beta-Hydroxysteroid dehydrogenase 4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
17-beta-Hydroxysteroid dehydrogenase 4 (HSD17B4) |
| Short name: |
17-beta-Hydroxysteroid dehydrogenase 4 Antibody (HSD17B4) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
17-b-Hydroxysteroid dehydrogenase 4 (Antibody to) (HSD17B4) |
| Alternative technique: |
antibodies |
| Identity: |
5213 |
| Gene: |
HSD17B4 |
More about : HSD17B4 |
| Long gene name: |
hydroxysteroid 17-beta dehydrogenase 4 |
| Synonyms gene name: |
hydroxysteroid (17-beta) dehydrogenase 4 |
| Synonyms: |
MFE-2 DBP SDR8C1 |
| Synonyms name: |
17beta-estradiol dehydrogenase type IV peroxisomal multifunctional protein 2 17-beta-HSD IV 17-beta-hydroxysteroid dehydrogenase 4 D-bifunctional protein, member 1 , peroxisomal D-3-hydroxyacyl-CoA dehydratase 3-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase beta-keto-reductase beta-hydroxyacyl dehydrogenase short chain dehydrogenase/reductase family 8C, 7-alpha |
| Locus: |
5q23, 1 |
| Discovery year: |
1994-09-14 |
| Entrez gene record: |
3295 |
| Pubmed identfication: |
8938456 19027726 |
| RefSeq identity: |
NM_000414 |
| Classification: |
Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000128899 |