FKBP51 Antibody, Cy5.5 Conjugated

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Catalog number: bs-11269R-Cy5.5
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: FKBP51 Antibody, Cy5.5 Conjugated
Quantity: 0.1ml
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More details :

Long name: Cy5, 5 Conjugated, FKBP51 Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Cy5, 5, 5, Cy5
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: FKBP51
Specificity: This is a highly specific antibody against FKBP51
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic peptide derived from human FKBP51
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: FK506 and rapamycin (1), FKBP12, FKBP51 and FKBP52, FKBP51 and FKBP52 are two highly related proteins (5, FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids (5), FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, FKBP52, Several related immunophilins, The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGF?type I receptor, and by blocking T-cell activation and proliferation (7), and following ligand binding, are characterized as cytosolic FK506-binding proteins, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6, known also as FKBP-59 or heat shock protein 56, such as cyclosporin, they functionally inhibit the phosphatase activity of calcineurin (2, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGF?pathway (4), 3), 6), 8), The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 675nm/694nm
Synonyms: FKBP51 FKBP54 PPIase P54 Ptg-10
Properties: Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated: These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene target: FKBP51 Conjugated
Short name: Conjugated, FKBP51 Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: 5, Cy5
Alternative name: cyanine 5, 5 coupled, FKBP51 (Antibody to)
Alternative technique: antibodies
Identity: 3721
Gene: FKBP5 | More about : FKBP5
Long gene name: FK506 binding protein 5
Synonyms gene name: FK506-binding protein 5
Locus: 6p21, 31
Discovery year: 1997-06-09
GenBank acession: U42031
Entrez gene record: 2289
Pubmed identfication: 9001212
Classification: FKBP prolyl isomerases Tetratricopeptide repeat domain containing
Havana BLAST/BLAT: OTTHUMG00000014576

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