FKBP51 Antibody, ALEXA FLUOR 350

Catalog number:	bs-11269R-A350 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	FKBP51 Antibody, ALEXA FLUOR 350
Quantity:	100ul
Related search:	fkbp alexa antibody antibodies gene receptor shock

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Long name:	ALEXA FLUOR 350 Conjugated, FKBP51 Polyclonal Antibody
Also known as:	Anti-FKBP51 PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	FKBP51
Specificity:	This is a highly specific antibody against FKBP51
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FKBP51
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	FK506 and rapamycin (1), FKBP12, FKBP51 and FKBP52, FKBP51 and FKBP52 are two highly related proteins (5, FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids (5), FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, FKBP52, Several related immunophilins, The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGF?type I receptor, and by blocking T-cell activation and proliferation (7), and following ligand binding, are characterized as cytosolic FK506-binding proteins, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6, known also as FKBP-59 or heat shock protein 56, such as cyclosporin, they functionally inhibit the phosphatase activity of calcineurin (2, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGF?pathway (4), 3), 6), 8), The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Synonyms:	FKBP51 FKBP54 PPIase P54 Ptg-10
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	FKBP51
Short name:	FKBP51 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, FKBP51 (Antibody to)
Alternative technique:	antibodies
Identity:	3721
Gene:	FKBP5 | More about : FKBP5
Long gene name:	FK506 binding protein 5
Synonyms gene name:	FK506-binding protein 5
Locus:	6p21, 31
Discovery year:	1997-06-09
GenBank acession:	U42031
Entrez gene record:	2289
Pubmed identfication:	9001212
Classification:	FKBP prolyl isomerases Tetratricopeptide repeat domain containing
Havana BLAST/BLAT:	OTTHUMG00000014576

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