| Long name: |
FITC Conjugated, CCT2/TCP1 beta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCT2/TCP1 beta |
| Specificity: |
This is a highly specific antibody against CCT2/TCP1 beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CCT2/TCP1 beta |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CCT subunit levels also change throughout the cell cycle, CCT2 exhibits both actin and tubulin binding activities (6, CCT2 is the Î, Each CCT subunit is thought to perform a specific function during protein folding and assembly (5), Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15% of newly synthesized eukaryotic proteins (2), The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1), This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3), with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4), ², -subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress, 3) but the exact molecular function on this subunit remains uncertain, CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Cctb |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCT2/TCP1 beta Conjugated |
| Short name: |
FITC Conjugated, CCT2/TCP1 beta Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CCT2/TCP1 b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1615 |
| Gene: |
CCT2 |
More about : CCT2 |
| Long gene name: |
chaperonin containing TCP1 subunit 2 |
| Synonyms gene name: |
chaperonin containing TCP1, subunit 2 (beta) |
| Locus: |
12q15 |
| Discovery year: |
1999-02-26 |
| GenBank acession: |
AF026293 |
| Entrez gene record: |
10576 |
| Pubmed identfication: |
9819444 |
| RefSeq identity: |
NM_006431 |
| Classification: |
Chaperonins |
| Havana BLAST/BLAT: |
OTTHUMG00000169383 |