| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CCT2/TCP1 beta |
| Specificity: |
This antibody reacts specifically with CCT2/TCP1 beta |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CCT2/TCP1 beta |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CCT subunit levels also change throughout the cell cycle, CCT2 exhibits both actin and tubulin binding activities (6, CCT2 is the Î, Each CCT subunit is thought to perform a specific function during protein folding and assembly (5), Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15% of newly synthesized eukaryotic proteins (2), The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1), This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3), with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4), ², -subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress, 3) but the exact molecular function on this subunit remains uncertain, CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Cctb |
| Also known as: |
CCT2/TCP1 beta Polyclonal Antibody |
| Other name: |
Anti-CCT2/TCP1 beta Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CCT2/TCP1 beta |
| Short name: |
Anti-CCT2/TCP1 beta (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CCT2/TCP1 b (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1615 |
| Gene: |
CCT2 |
More about : CCT2 |
| Long gene name: |
chaperonin containing TCP1 subunit 2 |
| Synonyms gene name: |
chaperonin containing TCP1, subunit 2 (beta) |
| Locus: |
12q15 |
| Discovery year: |
1999-02-26 |
| GenBank acession: |
AF026293 |
| Entrez gene record: |
10576 |
| Pubmed identfication: |
9819444 |
| RefSeq identity: |
NM_006431 |
| Classification: |
Chaperonins |
| Havana BLAST/BLAT: |
OTTHUMG00000169383 |