| Long name: |
CCT2/TCP1 beta Primary Polyclonal Antibody |
| Also known as: |
CCT2/TCP1 beta PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CCT2/TCP1 beta |
| Specificity: |
This is a highly specific antibody against CCT2/TCP1 beta |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CCT2/TCP1 beta |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CCT subunit levels also change throughout the cell cycle, CCT2 exhibits both actin and tubulin binding activities (6, CCT2 is the Î, Each CCT subunit is thought to perform a specific function during protein folding and assembly (5), Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15% of newly synthesized eukaryotic proteins (2), The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1), This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3), with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4), ², -subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress, 3) but the exact molecular function on this subunit remains uncertain, CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
99D8, CCT beta, CCT-2, CCT-beta, CCTB, CTP:phosphocholine cytidylyltransferase 2, Chaperonin containing TCP1 subunit 2, Chaperonin containing TCP1 subunit 2 beta, Chaperonin containing t complex polypeptide 1 beta subunit, Chaperonin containing t complex polypeptide 1 subunit 2, MGC142074, MGC142076, MGC94480, PRO1633, T complex protein 1 beta subunit, T complex protein 1 subunit beta, T-complex protein 1 subunit beta, TCP 1 beta, TCP-1-beta, TCPB_HUMAN, 1, CCT 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCT2/TCP1 beta |
| Short name: |
CCT2/TCP1 beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CCT2/TCP1 b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1615 |
| Gene: |
CCT2 |
More about : CCT2 |
| Long gene name: |
chaperonin containing TCP1 subunit 2 |
| Synonyms gene name: |
chaperonin containing TCP1, subunit 2 (beta) |
| Synonyms: |
Cctb |
| Locus: |
12q15 |
| Discovery year: |
1999-02-26 |
| GenBank acession: |
AF026293 |
| Entrez gene record: |
10576 |
| Pubmed identfication: |
9819444 |
| RefSeq identity: |
NM_006431 |
| Classification: |
Chaperonins |
| Havana BLAST/BLAT: |
OTTHUMG00000169383 |