| Long name: |
ALEXA FLUOR 488 Conjugated, CCT2/TCP1 beta Polyclonal Antibody |
| Also known as: |
Anti-CCT2/TCP1 beta PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCT2/TCP1 beta |
| Specificity: |
This is a highly specific antibody against CCT2/TCP1 beta |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CCT2/TCP1 beta |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CCT subunit levels also change throughout the cell cycle, CCT2 exhibits both actin and tubulin binding activities (6, CCT2 is the Î, Each CCT subunit is thought to perform a specific function during protein folding and assembly (5), Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15% of newly synthesized eukaryotic proteins (2), The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1), This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3), with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4), ², -subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress, 3) but the exact molecular function on this subunit remains uncertain, CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
Cctb |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CCT2/TCP1 beta Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CCT2/TCP1 beta |
| Short name: |
CCT2/TCP1 beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, CCT2/TCP1 b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1615 |
| Gene: |
CCT2 |
More about : CCT2 |
| Long gene name: |
chaperonin containing TCP1 subunit 2 |
| Synonyms gene name: |
chaperonin containing TCP1, subunit 2 (beta) |
| Locus: |
12q15 |
| Discovery year: |
1999-02-26 |
| GenBank acession: |
AF026293 |
| Entrez gene record: |
10576 |
| Pubmed identfication: |
9819444 |
| RefSeq identity: |
NM_006431 |
| Classification: |
Chaperonins |
| Havana BLAST/BLAT: |
OTTHUMG00000169383 |