| Long name: |
HRP Conjugated, Microcephalin 1/BRIT1 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Microcephalin 1/BRIT1 |
| Specificity: |
This is a highly specific antibody against Microcephalin 1/BRIT1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Microcephalin 1/BRIT1 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Human Microcephalin contains three BRCA1 C-terminal (BRCT) domains and shares 57% identity with its mouse ortholog, It functions in DNA damage response and regulation of cell cycle checkpoints, Microcephalin displays significantly higher rates of protein evolution in primates than in rodents, Microcephalin has a very young, Predominant expression of human Microcephalin is observed in fetal brain, although the nature of the positive selection is poorly understood, liver and kidney tissues and is expressed during neurogenesis in mice, polymorphism haplotype associated with modern humans, single nucleotide, the most conserved regions being BRCT domains where there is 80% identity, this gene is presumably still evolving in Homo sapiens, this trend is most noticeable for the subset of genes associated with nervous system development, Microcephalin modulates brain size and has been proliferating under strong positive selection for several thousand years |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
FLJ12847 BRIT1 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
Microcephalin 1/BRIT1 Conjugated |
| Short name: |
Conjugated, Microcephalin 1/BRIT1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, Microcephalin 1/BRIT1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6954 |
| Gene: |
MCPH1 |
More about : MCPH1 |
| Long gene name: |
microcephalin 1 |
| Synonyms gene name: |
microcephaly, primary autosomal recessive 1 |
| Synonyms name: |
BRCT-repeat inhibitor of TERT expression 1 |
| Locus: |
8p23, 1 |
| Discovery year: |
1998-02-11 |
| GenBank acession: |
AK022909 |
| Entrez gene record: |
79648 |
| Pubmed identfication: |
9683597 17925396 |
| RefSeq identity: |
NM_024596 |
| Havana BLAST/BLAT: |
OTTHUMG00000163618 |