Microcephalin 1/BRIT1 Antibody, Cy7 Conjugated

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Catalog number: bs-11227R-Cy7
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: Microcephalin 1/BRIT1 Antibody, Cy7 Conjugated
Quantity: 0.1ml
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More details :

Long name: Cy7 Conjugated, Microcephalin 1/BRIT1 Antibody
Category: Conjugated Primary Antibodies
Conjugation: Cy7
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: Microcephalin 1/BRIT1
Specificity: This is a highly specific antibody against Microcephalin 1/BRIT1
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic peptide derived from human Microcephalin 1/BRIT1
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Human Microcephalin contains three BRCA1 C-terminal (BRCT) domains and shares 57% identity with its mouse ortholog, It functions in DNA damage response and regulation of cell cycle checkpoints, Microcephalin displays significantly higher rates of protein evolution in primates than in rodents, Microcephalin has a very young, Predominant expression of human Microcephalin is observed in fetal brain, although the nature of the positive selection is poorly understood, liver and kidney tissues and is expressed during neurogenesis in mice, polymorphism haplotype associated with modern humans, single nucleotide, the most conserved regions being BRCT domains where there is 80% identity, this gene is presumably still evolving in Homo sapiens, this trend is most noticeable for the subset of genes associated with nervous system development, Microcephalin modulates brain size and has been proliferating under strong positive selection for several thousand years
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 743nm/767nm
Synonyms: FLJ12847 BRIT1
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated: These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene target: Microcephalin 1/BRIT1 Conjugated
Short name: Conjugated, Microcephalin 1/BRIT1 Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Cy7
Alternative name: cyanine 7 coupled, Microcephalin 1/BRIT1 (Antibody to)
Alternative technique: antibodies
Identity: 6954
Gene: MCPH1 | More about : MCPH1
Long gene name: microcephalin 1
Synonyms gene name: microcephaly, primary autosomal recessive 1
Synonyms name: BRCT-repeat inhibitor of TERT expression 1
Locus: 8p23, 1
Discovery year: 1998-02-11
GenBank acession: AK022909
Entrez gene record: 79648
Pubmed identfication: 9683597 17925396
RefSeq identity: NM_024596
Havana BLAST/BLAT: OTTHUMG00000163618

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