| Long name: |
GPR49/LGR5 Primary Polyclonal Antibody |
| Also known as: |
GPR49/LGR5 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GPR49/LGR5 |
| Specificity: |
This is a highly specific antibody against GPR49/LGR5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
825-875/907 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse GPR49 |
| Gene ID number: |
14160 |
| Swiss Prot: |
Q9Z1P4 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In contrast to classical G-protein coupled receptors, Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development, RSPO2, RSPO3 or RSPO4), Upon binding to R-spondins (RSPO1, associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, does not activate heterotrimeric G-proteins to transduce the signal, triggering the canonical Wnt signaling pathway to increase expression of target genes, Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
G-protein coupled receptor 49, Gpr49, Leucine-rich repeat-containing G-protein coupled receptor 5, Lgr5, Orphan G-protein coupled receptor FEX, FEX |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPR49/LGR5 |
| Short name: |
GPR49/LGR5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GPR49/LGR5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4504 |
| Gene: |
LGR5 |
More about : LGR5 |
| Long gene name: |
leucine rich repeat containing G protein-coupled receptor 5 |
| Synonyms gene: |
GPR67 GPR49 |
| Synonyms gene name: |
G protein-coupled receptor 49 |
| Synonyms: |
HG38 FEX |
| Locus: |
12q21, 1 |
| Discovery year: |
1999-10-22 |
| GenBank acession: |
AF062006 |
| Entrez gene record: |
8549 |
| Pubmed identfication: |
9642114 |
| RefSeq identity: |
NM_003667 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000169543 |