| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LGR5 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IF, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the LGR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This LGR5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O75473 |
| Purity: |
Purified |
| Description: |
Expressed at the base of crypts in colonic and small mucosa stem cells, Expressed in skeletal muscle, In premalignant cancer expression is not restricted to the cript base, It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues, Overexpressed in cancers of the ovary, Stem cell marker of the intestinal epithelium and the hair follicle, Target gene of Wnt signaling, and various region of brain, colon and liver, placenta, spinal cord, LGR5/GPR49 is an orphan receptor |
| Immunogen: |
A portion of amino acids 238-270 from the human protein was used as the immunogen for this LGR5 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the LGR5 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
LGR5 |
| Short name: |
LGR5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
LGR5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4504 |
| Gene: |
LGR5 |
More about : LGR5 |
| Long gene name: |
leucine rich repeat containing G protein-coupled receptor 5 |
| Synonyms gene: |
GPR67 GPR49 |
| Synonyms gene name: |
G protein-coupled receptor 49 |
| Synonyms: |
HG38 FEX |
| Locus: |
12q21, 1 |
| Discovery year: |
1999-10-22 |
| GenBank acession: |
AF062006 |
| Entrez gene record: |
8549 |
| Pubmed identfication: |
9642114 |
| RefSeq identity: |
NM_003667 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000169543 |