| Long name: |
Biotin Conjugated, Keratocan Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Keratocan |
| Specificity: |
This is a highly specific antibody against Keratocan |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Keratocan |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Biglycan, Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), Fibromod-ulin, Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness, Keratocan, Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure, Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains, Keratocan is mainly detected in the cornea, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta, The Decorin core protein binds to growth factors, an autosomal recessive disorder where the forward convex curvature of the cornea is flattened, and to the Decorin endocytosis receptor, but can also be expressed in trachea, intercellular matrix molecules such as Fibronectin and Throm-bospondin, intestine, lung and skeletal muscle, ovary, Small leucine-rich proteoglycans (SLRPs) such as Decorin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KERA, KERA_HUMAN, KTN, Keratan sulfate proteoglycan keratocan, Keratocan, SLRR2B, CNA2 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Keratocan Conjugated |
| Short name: |
Conjugated, Keratocan Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Keratocan (Antibody to) |
| Alternative technique: |
antibodies |