| Long name: |
ALEXA FLUOR 594 Conjugated, Keratocan Polyclonal Antibody |
| Also known as: |
Anti-Keratocan PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Keratocan |
| Specificity: |
This is a highly specific antibody against Keratocan |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Keratocan |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Biglycan, Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), Fibromod-ulin, Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness, Keratocan, Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure, Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains, Keratocan is mainly detected in the cornea, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta, The Decorin core protein binds to growth factors, an autosomal recessive disorder where the forward convex curvature of the cornea is flattened, and to the Decorin endocytosis receptor, but can also be expressed in trachea, intercellular matrix molecules such as Fibronectin and Throm-bospondin, intestine, lung and skeletal muscle, ovary, Small leucine-rich proteoglycans (SLRPs) such as Decorin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SLRR2B |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
Keratocan |
| Short name: |
Keratocan Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, Keratocan (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6309 |
| Gene: |
KERA |
More about : KERA |
| Long gene name: |
keratocan |
| Synonyms gene: |
CNA2 |
| Synonyms name: |
keratocan proteoglycan |
| Locus: |
12q21, 33 |
| Discovery year: |
1999-08-26 |
| GenBank acession: |
AF063301 |
| Entrez gene record: |
11081 |
| Pubmed identfication: |
10565548 10802664 |
| RefSeq identity: |
NM_007035 |
| Classification: |
Small leucine rich repeat proteoglycans |
| Havana BLAST/BLAT: |
OTTHUMG00000170073 |
| Locus Specific Databases: |
LRG_538 |