| Long name: |
ALEXA FLUOR 647 Conjugated, Bestrophin Polyclonal Antibody |
| Also known as: |
Anti-Bestrophin PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Bestrophin |
| Specificity: |
This is a highly specific antibody against Bestrophin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bestrophin |
| Gene ID Number: |
5068 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Best disease is frequently a reflection of mutations in the Bestrophin gene, Bestrophin Bestrophin 2, Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium, Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision, known as Best disease, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells, Best vitelliform macular dystrophy, Bestrophin 3 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Bestrophin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Bestrophin |
| Short name: |
Bestrophin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Bestrophin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17106 |
| Gene: |
BEST4 |
More about : BEST4 |
| Long gene name: |
bestrophin 4 |
| Synonyms gene: |
VMD2L2 |
| Synonyms gene name: |
vitelliform macular dystrophy 2-like 2 |
| Locus: |
1p34, 1 |
| Discovery year: |
2003-12-03 |
| GenBank acession: |
AF440757 |
| Entrez gene record: |
266675 |
| Pubmed identfication: |
12032738 16702355 |
| RefSeq identity: |
NM_153274 |
| Classification: |
Bestrophins |
| Havana BLAST/BLAT: |
OTTHUMG00000008488 |