| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Bestrophin 4 |
| Specificity: |
This antibody reacts specifically with Bestrophin 4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Bestrophin 4 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane, Bestrophin-4 is predominantly expressed in the colon, It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels, but can be found at low levels in testis, lung and retina, placenta, spinal chord, such as bicarbonate, trachea, Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Bestrophin 4 Polyclonal Antibody |
| Other name: |
Anti-Bestrophin 4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Bestrophin 4 |
| Short name: |
Anti-Bestrophin 4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Bestrophin 4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17106 |
| Gene: |
BEST4 |
More about : BEST4 |
| Long gene name: |
bestrophin 4 |
| Synonyms gene: |
VMD2L2 |
| Synonyms gene name: |
vitelliform macular dystrophy 2-like 2 |
| Locus: |
1p34, 1 |
| Discovery year: |
2003-12-03 |
| GenBank acession: |
AF440757 |
| Entrez gene record: |
266675 |
| Pubmed identfication: |
12032738 16702355 |
| RefSeq identity: |
NM_153274 |
| Classification: |
Bestrophins |
| Havana BLAST/BLAT: |
OTTHUMG00000008488 |