| Long name: |
ALEXA FLUOR 647 Conjugated, TSPAN12 Polyclonal Antibody |
| Also known as: |
Anti-TSPAN12 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TSPAN12 |
| Specificity: |
This is a highly specific antibody against TSPAN12 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
34-50/305 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TSPAN12 |
| Gene ID Number: |
23554 |
| Swiss Prot: |
O95859 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP), Activates MMP14/MT1-MMP-dependent cleavage activity, Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP, Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction, Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity), while it does not activate the Wnt-dependent activation of FZD4, Regulator of cell surface receptor signal transduction |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
NET-2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the TSPAN12 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
TSPAN12 |
| Short name: |
TSPAN12 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, TSPAN12 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21641 |
| Gene: |
TSPAN12 |
More about : TSPAN12 |
| Long gene name: |
tetraspanin 12 |
| Synonyms gene: |
TM4SF12 |
| Synonyms gene name: |
transmembrane 4 superfamily member 12 |
| Locus: |
7q31, 31 |
| Discovery year: |
2003-07-21 |
| GenBank acession: |
AF124522 |
| Entrez gene record: |
23554 |
| RefSeq identity: |
NM_012338 |
| Classification: |
Tetraspanins |
| Havana BLAST/BLAT: |
OTTHUMG00000156980 |