| Long name: |
Cy5 Conjugated, TSPAN12 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TSPAN12 |
| Specificity: |
This is a highly specific antibody against TSPAN12 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
34-50/305 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human TSPAN12 |
| Gene ID number: |
23554 |
| Swiss Prot: |
O95859 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP), Activates MMP14/MT1-MMP-dependent cleavage activity, Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP, Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction, Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity), while it does not activate the Wnt-dependent activation of FZD4, Regulator of cell surface receptor signal transduction |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
NET-2 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TSPAN12 Conjugated |
| Short name: |
Conjugated, TSPAN12 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, TSPAN12 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21641 |
| Gene: |
TSPAN12 |
More about : TSPAN12 |
| Long gene name: |
tetraspanin 12 |
| Synonyms gene: |
TM4SF12 |
| Synonyms gene name: |
transmembrane 4 superfamily member 12 |
| Locus: |
7q31, 31 |
| Discovery year: |
2003-07-21 |
| GenBank acession: |
AF124522 |
| Entrez gene record: |
23554 |
| RefSeq identity: |
NM_012338 |
| Classification: |
Tetraspanins |
| Havana BLAST/BLAT: |
OTTHUMG00000156980 |