TSPAN12 Antibody

Catalog number:	bs-10425R Buy Now
Price:	729 €
Supplier:	genways
Product name:	TSPAN12 Antibody
Quantity:	1 tube
Other quantities:	1 vial 521€
Related search:	tspan antibody gene antibodies net synonyms accumulation

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Long name:	TSPAN12 Primary Polyclonal Antibody
Also known as:	TSPAN12 PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	TSPAN12
Specificity:	This is a highly specific antibody against TSPAN12
Modification(s):	None
Modification site(s):	Unmodified antibody
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	34-50/305
Subcellular location:	Extracellular
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TSPAN12
Gene ID number:	23554
Swiss Prot:	O95859
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP), Activates MMP14/MT1-MMP-dependent cleavage activity, Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP, Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction, Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity), while it does not activate the Wnt-dependent activation of FZD4, Regulator of cell surface receptor signal transduction
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	NET-2, NET2, TM4SF12, TSPAN12, Tetraspan NET-2, Tetraspanin-12, Transmembrane 4 superfamily member 12, Tspan-12, UNQ774/PRO1568, EVR5
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	TSPAN12
Short name:	TSPAN12 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	TSPAN12 (Antibody to)
Alternative technique:	antibodies
Identity:	21641
Gene:	TSPAN12 | More about : TSPAN12
Long gene name:	tetraspanin 12
Synonyms gene:	TM4SF12
Synonyms gene name:	transmembrane 4 superfamily member 12
Synonyms:	NET-2
Locus:	7q31, 31
Discovery year:	2003-07-21
GenBank acession:	AF124522
Entrez gene record:	23554
RefSeq identity:	NM_012338
Classification:	Tetraspanins
Havana BLAST/BLAT:	OTTHUMG00000156980

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