| Catalog number: | bs-10425R-A350 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | TSPAN12 Antibody, ALEXA FLUOR 350 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 350 Conjugated, TSPAN12 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-TSPAN12 PAb ALEXA FLUOR 350 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 350, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | TSPAN12 |
| Specificity: | This is a highly specific antibody against TSPAN12 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 34-50/305 |
| Subcellular location: | Extracellular |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TSPAN12 |
| Gene ID Number: | 23554 |
| Swiss Prot: | O95859 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP), Activates MMP14/MT1-MMP-dependent cleavage activity, Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP, Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction, Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity), while it does not activate the Wnt-dependent activation of FZD4, Regulator of cell surface receptor signal transduction |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 343nm/442nm |
| Synonyms: | NET-2 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 350, Alexa Fluor |
| Gene target: | TSPAN12 |
| Short name: | TSPAN12 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 350 |
| Alternative name: | ALEXA FLUOR 350, TSPAN12 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 21641 |
| Gene: | TSPAN12 | More about : TSPAN12 |
| Long gene name: | tetraspanin 12 |
| Synonyms gene: | TM4SF12 |
| Synonyms gene name: | transmembrane 4 superfamily member 12 |
| Locus: | 7q31, 31 |
| Discovery year: | 2003-07-21 |
| GenBank acession: | AF124522 |
| Entrez gene record: | 23554 |
| RefSeq identity: | NM_012338 |
| Classification: | Tetraspanins |
| Havana BLAST/BLAT: | OTTHUMG00000156980 |
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