Ron (Tyr1238+Tyr1239) Antibody, Biotin Conjugated

Catalog number:	bs-10118R-Biotin Buy Now
Price:	370 €
Supplier:	MBS Polyclonals_1
Product name:	Ron (Tyr1238+Tyr1239) Antibody, Biotin Conjugated
Quantity:	100ug
Related search:	ron antibody tyrtyr antibodies biotin cell migration receptor protein

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Long name:	Biotin Conjugated, Ron (Tyr1238+Tyr1239) Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Ron Tyr1238+Tyr1239
Specificity:	This is a highly specific antibody against Ron Tyr1238+Tyr1239
Modification:	Phosphorylation
Modification site:	Tyr1238+Tyr1239
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	1235-1245/1400
Subcellular location:	Cell membrane
Source:	KLH conjugated synthetic phosphopeptide derived from human MST1R around the phosphorylation site of Tyr1238+Tyr1239
Gene ID number:	4486
Swiss Prot:	Q04912
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Alternatively, Following activation by ligand, Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules, PI3 kinase-AKT, PLCG1 or the adapter GAB1, Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand, RON signaling activates the wound healing response by promoting epithelial cell migration, Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, Regulates many physiological processes including cell survival, interacts with the PI3-kinase subunit PIK3R1, migration and differentiation, or PLCgamma-PKC, proliferation as well as survival at the wound site, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	CD136, CDw136, MSP receptor, MST1R, Macrophage-stimulating protein receptor, PTK8, Protein-tyrosine kinase 8, p185-Ron, RON
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	Ron (Tyr1238+Tyr1239) Conjugated
Short name:	Conjugated, Ron (Tyr1238+Tyr1239) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, Ron (Tyr1238+Tyr1239) (Antibody to)
Alternative technique:	antibodies

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