Ron (Tyr1238+Tyr1239) Antibody, ALEXA FLUOR 555

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Catalog number: bs-10118R-A555
Price: 370 €
Supplier: MBS Polyclonals_1
Product name: Ron (Tyr1238+Tyr1239) Antibody, ALEXA FLUOR 555
Quantity: 100ug
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Long name: ALEXA FLUOR 555 Conjugated, Ron (Tyr1238+Tyr1239) Antibody
Also known as: Anti-Ron Tyr1238+Tyr1239 PAb ALEXA FLUOR 555
Category: Conjugated Primary Antibodies
Conjugated with: 555, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: Ron Tyr1238+Tyr1239
Specificity: This is a highly specific antibody against Ron Tyr1238+Tyr1239
Modification: Phosphorylation
Modification Site: Tyr1238+Tyr1239
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 1235-1245/1400
Subcellular location: Cell membrane
Source: KLH conjugated synthetic phosphopeptide derived from human MST1R around the phosphorylation site of Tyr1238+Tyr1239
Gene ID Number: 4486
Swiss Prot: Q04912
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Alternatively, Following activation by ligand, Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules, PI3 kinase-AKT, PLCG1 or the adapter GAB1, Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand, RON signaling activates the wound healing response by promoting epithelial cell migration, Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, Regulates many physiological processes including cell survival, interacts with the PI3-kinase subunit PIK3R1, migration and differentiation, or PLCgamma-PKC, proliferation as well as survival at the wound site, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 553nm/568nm
Synonyms: CD136, CDw136, MSP receptor, MST1R, Macrophage-stimulating protein receptor, PTK8, Protein-tyrosine kinase 8, p185-Ron, RON
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 555, Alexa Fluor
Gene target: Ron (Tyr1238+Tyr1239)
Short name: Ron (Tyr1238+Tyr1239) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 555
Alternative name: ALEXA FLUOR 555, Ron (Tyr1238+Tyr1239) (Antibody to)
Alternative technique: antibodies

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