| Long name: |
Cy5 Conjugated, Ron (Tyr1238+Tyr1239) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Ron Tyr1238+Tyr1239 |
| Specificity: |
This is a highly specific antibody against Ron Tyr1238+Tyr1239 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr1238+Tyr1239 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1235-1245/1400 |
| Subcellular location: |
Cell membrane |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human MST1R around the phosphorylation site of Tyr1238+Tyr1239 |
| Gene ID number: |
4486 |
| Swiss Prot: |
Q04912 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Alternatively, Following activation by ligand, Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules, PI3 kinase-AKT, PLCG1 or the adapter GAB1, Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand, RON signaling activates the wound healing response by promoting epithelial cell migration, Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, Regulates many physiological processes including cell survival, interacts with the PI3-kinase subunit PIK3R1, migration and differentiation, or PLCgamma-PKC, proliferation as well as survival at the wound site, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
CD136, CDw136, MSP receptor, MST1R, Macrophage-stimulating protein receptor, PTK8, Protein-tyrosine kinase 8, p185-Ron, RON |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Ron (Tyr1238+Tyr1239) Conjugated |
| Short name: |
Conjugated, Ron (Tyr1238+Tyr1239) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, Ron (Tyr1238+Tyr1239) (Antibody to) |
| Alternative technique: |
antibodies |