HPV16 E6 protein Antibody, ALEXA FLUOR 555

Catalog number:	bs-0990R-A555 Buy Now
Price:	630 €
Supplier:	acr
Product name:	HPV16 E6 protein Antibody, ALEXA FLUOR 555
Quantity:	0,1 ml
Related search:	protein alexa hpv antibody antibodies human cell deg

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Long name:	ALEXA FLUOR 555 Conjugated, HPV16 E6 protein Polyclonal Antibody
Also known as:	Anti-HPV16 E6 protein PAb ALEXA FLUOR 555
Category:	Conjugated Primary Antibodies
Conjugated with:	555, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	HPV16 E6 protein
Specificity:	This is a highly specific antibody against HPV16 E6 protein
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	100-150/158
Subcellular location:	Nucleus
Source:	synthetic peptide from HPV16-E6 conjugated to KLH
Gene ID Number:	1489078
Swiss Prot:	P03126
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Virus
Cross-reactive species details:	HPV16
Background of the antigen:	Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development, E6 also inhibits immune response by interacting with host IRF3 and TYK2, E6 associates with host E6-AP ubiquitin-protein ligase, Fas-associated death domain-containing protein (FADD) and procaspase 8, In turn, Other cellular targets including Bak, The complex E6/E6P targets several other substrates to degradation via the proteasome including host NFX1-91, The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization, These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway, a repressor of human telomerase reverse transcriptase (hTERT), and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation, are degraded by E6/E6AP causing inhibition of apoptosis, Plays a major role in the induction and maintenance of cellular transformation
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	553nm/568nm
Synonyms:	E6 protein, HPV16 E6, HPV16 E6 protein, HPV16-E6, Human Papilloma Virus, Human papillomavirus type 16, Human papillomavirus type 16 E6, Protein E6, VE6_HPV16, E6
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 555, Alexa Fluor
Gene target:	HPV16 E6 protein
Short name:	HPV16 E6 protein Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 555
Alternative name:	ALEXA FLUOR 555, HPV16 E6 protein (Antibody to)
Alternative technique:	antibodies

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