| Catalog number: | GENTAUR-58be5a744688e |
|---|---|
| Price: | 732 € |
| Supplier: | acr |
| Product name: | Anti-HPV16-E7 (Polyclonal), ALEXA Fluor 594 |
| Quantity: | 1 mg |
| Related search: |
| Type: | Conjugated Primary Antibody |
|---|---|
| Conjugated with: | 594, ALEXA FLUOR® |
| Host organism: | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: | HPV16-E7 |
| Specificity: | This antibody reacts specifically with HPV16-E7 |
| Modification: | No modification has been applied to this antibody |
| Modification site: | None |
| Clonality: | Polyclonal Antibody |
| Clone: | Polyclonal Antibodies |
| Concentration: | 1ug per 1ul |
| Antigen Source: | KLH conjugated synthetic peptide derived from middle of HPV16-E7 |
| Gene ID: | 1489079 |
| Applications: | IF(IHC-P) |
| Applications with corresponding dilutions: | IF(IHC-P)(1:50-200) |
| Cross reactive species: | Virus |
| Cross Reactive Species details: | HPV16 |
| Background information: | Approximately 90% of cervical cancers contain HPV DNA of the high risk types, HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types, Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function, The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, The specific interactions of the E6 and E7 proteins with p53 and pRB, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro, correlate with HPV high and low risk classifications, respectively, Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer |
| Purification method: | Purified by Protein A |
| Storage: | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | E7 protein HPV16, HPV16 E7, Human Papilloma Virus, Human Papillomavirus 16 E7, Human papillomavirus type 16 E7, Human papillomavirus type 16 E7, Protein E7, VE7_HPV16, E7 |
| Also known as: | HPV16-E7 Polyclonal Antibody |
| Other name: | Anti-HPV16-E7 Polyclonal |
| Advisory: | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: | For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Group: | Polyclonals and antibodies |
| About: | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: | HPV16-E7 |
| Short name: | Anti-HPV16-E7 (Polyclonal) Fluor 594 |
| Technique: | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label: | ALEXA |
| Alternative name: | ALEXA Fluor 594, antibody to-HPV16-E7 (polyclonal) |
| Alternative technique: | polyclonals |
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