| Long name: |
FITC Conjugated, TRIM32/BBS11 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRIM32/BBS11 |
| Specificity: |
This is a highly specific antibody against TRIM32/BBS11 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse TRIM32 |
| Gene ID number: |
22954 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Additionally, Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM), TRIM32, TRIM32 has six C-terminal NHL domains, TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), The TRIM32 gene encodes an E3 ubiquitin ligase, UbcH5c and UbcH6, a RING-finger and a coiled-coil motif, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, an autosomal recessive disorder characterized by pigmentary retinopathy, contains a domain structure composed of a B-box, hypogenitalism, it is expressed mainly in the skeletal muscle, learning disabilities and obesity, like all TRIM proteins, polydactyly, renal abnormalities, Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HT2A TATIP BBS11 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TRIM32/BBS11 Conjugated |
| Short name: |
FITC Conjugated, TRIM32/BBS11 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TRIM32/BBS11 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16380 |
| Gene: |
TRIM32 |
More about : TRIM32 |
| Long gene name: |
tripartite motif containing 32 |
| Synonyms gene: |
LGMD2H |
| Synonyms gene name: |
limb girdle muscular dystrophy 2H (autosomal recessive) tripartite motif-containing 32 |
| Locus: |
9q33, 1 |
| Discovery year: |
2001-08-10 |
| GenBank acession: |
U18543 |
| Entrez gene record: |
22954 |
| Pubmed identfication: |
11331580 7778269 16606853 |
| RefSeq identity: |
NM_012210 |
| Classification: |
Tripartite motif containing Ring finger proteins Bardet-Biedl syndrome associated |
| Havana BLAST/BLAT: |
OTTHUMG00000021026 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_211 |